Two Killed in Mesa Crash Involving School Bus; Southern Avenue Closed in Both Directions

Mesa police investigate a fatal collision involving a school bus and passenger vehicle near Southern Avenue and 80th Street in Mesa, Arizona, on November 6, 2026.
2 Killed in Mesa School Bus Crash on Southern Avenue / iSkyNews.com

Two adults were killed in a crash involving a school bus near Southern Avenue and 80th Street in Mesa. No students were aboard. Road closures remain in effect.

By Ciara Perez, Senior Multimedia Correspondent

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MESA, AZ (November 6, 2026) — Two people were killed Friday afternoon following a serious collision involving a school bus and a passenger vehicle in east Mesa, according to the Mesa Police Department.

The crash occurred at approximately 4:30 p.m. near East Southern Avenue and South 80th Street.

According to Detective Jose Aguirre, Public Information Officer for the Mesa Police Department, officers responded to reports of a two-vehicle collision involving a school bus and a passenger vehicle.

Both adult occupants of the passenger vehicle sustained fatal injuries and were pronounced dead at the scene.

The school bus driver was transported to a local hospital for medical treatment. His condition has not been released.

Police confirmed that no students were aboard the school bus when the collision occurred.

Southern Avenue Road Closures

The fatal crash has prompted significant traffic closures as investigators continue working at the scene.

Westbound Southern Avenue is closed at Hawes Road, while eastbound Southern Avenue is also closed at Sossaman Road.

Motorists are urged to avoid the area and use alternate routes while emergency personnel investigate the crash.

Investigation Ongoing

Mesa police officers remain at the scene investigating the circumstances surrounding the collision.

Authorities have not released the identities of the two deceased occupants, and the cause of the crash remains under investigation.

Additional information regarding the vehicles involved and the events leading up to the collision has not yet been released.

iSkyNews.com will continue monitoring this developing story and provide updates as additional information becomes available.

Follow the incident on Citizen:
https://go.citizen.com/bpXfMYbmR7b

Source: Mesa Police Department — Detective Jose Aguirre, Public Information Officer.

Our thoughts and prayers are with the families and everyone affected by today’s tragic collision, including the first responders who faced such a difficult scene.

We also want to extend our sincere appreciation to the men and women of the Mesa Police Department and Mesa Fire & Medical for their continued professionalism, dedication, and commitment to keeping our community safe. Thank you for everything you do, especially during moments like these. - iSkyNews.com Staff

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Mesa fatal crash, Mesa school bus accident, Southern Avenue crash, Hawes Road closure, Sossaman Road closure, Mesa Police Department, Mesa Arizona breaking news, November 6 2026, iSkyNews

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